INTERMITTENT DIETARY METHIONINE DEPRIVATION FACILITATES TUMORAL FERROPTOSIS AND SYNERGIZES WITH CHECKPOINT BLOCKADE

Intermittent dietary methionine deprivation facilitates tumoral ferroptosis and synergizes with checkpoint blockade

Abstract Dietary methionine interventions are beneficial to apoptosis-inducing chemotherapy and radiotherapy for cancer, while their effects on ferroptosis-targeting therapy and immunotherapy are unknown.Here we show the length of time methionine deprivation affects tumoral ferroptosis differently.Prolonged methionine deprivation prevents glutathio

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A dataset of cold-water coral distribution records

Species distribution data are key for monitoring present and future biodiversity patterns and informing conservation and management strategies.Large biodiversity information facilities often contain spatial and taxonomic errors that reduce the quality of the provided data.Moreover, datasets are frequently shared in varying formats, inhibiting prope

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